Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis.


06 Nov 2018 09:21 Ricerca


Deriving from the Greek word ?????? for “tree moss” and the Latin word planus for “planar,” lichen planus is a relatively uncommon and heterogeneous cutaneous disorder that typically develops in middle-aged adults. Despite the significant clinical burden associated with the disorder, little well-conducted molecular research has been undertaken, possibly because of heterogeneity impeding consistent and confident phenotyping.

The multiple variants of lichenoid disease bear overlapping clinical and pathologic features despite manifesting as distinct clinical disorders.

The first article in this 2-part continuing medical education series provides a comprehensive overview of the clinical and pathologic characteristics of cutaneous lichenoid dermatoses and links these manifestations to recent advances in our understanding of the underlying pathobiology of such diseases.

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Approfondimenti

FonteJournal of the American Academy of Dermatology
Titolo originaleLichen planus and lichenoid dermatoses
AutoriChristos Tziotzios, John Y.W. Lee, Timothy Brier, Ryo Saito, Chao-Kai Hsu, Kapil Bhargava, Catherine M. Stefanato, David A. Fenton, John A. McGrath
Link fonteLink articolo originale
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