Guideline on the Diagnosis and Treatment of Autoimmune bullous diseases: Pemphigus

01 Sep 2014 12:44 Linee guida

Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localised or generalised bullous lesions. In up to 20% of affected patients bullae may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged.

This guideline for the treatment of bullous pemphigoid has been developed under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarises evidence-based and expert-based recommendations (S2 level).

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