Contact dermatitis and atopic dermatitis- Two tales, an interwoven story


22 Jan 2019 11:23 Ricerca


Atopic dermatitis is a multifactorial disease that can concomitantly occur with irritant and allergic contact dermatitis.

The colloquial use of atopic dermatitis and eczema interchangeably has created confusion among patients and providers alike. Atopic skin is a complex entity that involves a defective barrier and biome, an aberrant immune response, and abnormal neural activation, while eczema is a generalized term denoting a particular appearance common to multiple diagnoses including atopic dermatitis and contact dermatitis.

The conventional paradigm that simplifies atopic dermatitis and allergic contact dermatitis into distinct Th2 and Th1 processes, respectively, fails to acknowledge potential immunologic intersection points and contributes to impaired disease management. This article will review the complex interplay of atopic dermatitis and contact dermatitis and discuss treatment strategies for recalcitrant cases.

Inserito da segreteria SIDeMaST

Approfondimenti

FonteGiornale Italiano Dermatologia Venereologia
Titolo originaleContact dermatitis and atopic dermatitis- Two tales, an interwoven story
AutoriG. Alden HOLMES, Janna VASSANTACHART, Calvin T. SUNG, Alina GOLDENBERG, Sharon E. JACOB
Link fonteLink articolo originale
Argomenti correlati allergie eczema

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